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Scientific Publications

Selected Publications by Affectis and its partners

Schweizer M.C., Henniger M.S.H., and Sillaber I. (2009) Chronic Mild Stress (CMS) in Mice: Of Anhedonia, ‘Anomalous Anxiolysis’ and Activity. PLoS ONE 4:e4326-e4336

Sillaber I., Panhuysen M., et al. (2008) Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetine. Psychopharmacol 200:557-572

Paez-Pereda M. and Panhuysen M. (2008) Strategies to identify biomarkers for depression. Biomarkers for Psychiatric Disorders. Ed. C.W. Turck, Elsevier

Sillaber I., Holsboer F., Wotjak C.T. (2008) Animal models of mood disorders. Neurobiology of Mental Illness, 3rd edition (NMI-3), Charney DS, Nestler EJ (eds). Oxford University Press, San Francisco, 378-391

Barden N. et al. (2006) Analysis of Single Nucleotide Polymorphisms in Genes in the Chromosome 12Q24.31 Region Points to P2RX7 as a Susceptibility Gene to Bipolar Affective Disorder. Am J Med Genet B 141:347-382

Lucae S. et al. (2006) P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorders. Hum Mol Genet 15:2438-2445

Müller N. et al. (2006) The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine. Mol Psychiatry 11:680-684

Paez-Pereda M. (2005) New drug targets in the signaling pathways activated by antidepressants. Prog Neuropsychopharmacol Biol Psychiatry 29:1010-1016

Refojo D. et al. (2005) Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas. Proc Natl Acad Sci USA 102:6183-6188

Müller M.B. et al. (2003) Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress. Nat Neurosci 6:1100-1107

Sillaber I. et al. (2002) Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors. Science 296:931-933

Müller N. et al. (2002) Beneficial Antipsychotic Effects of Celecoxib Add-On Therapy Compared to Risperidone Alone in Schizophrenia. Am J Psych 156:1029-1034

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